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Esse mapa conceitual, produzido no IHMC CmapTools, tem a informação relacionada a: G6PD Deficiency, G6P is at the start of Pentose Phosphate Pathway, reduced Glutathione is an antioxidant, Reticulocyte Count 262 x 10^9/L contribute to diagnosis of deficiency of G6PD, Anemia stimulates erythropoiesis, High redox potential drugs can trigger Extravascular Hemolysis, Total Serum Bilirubin 19 mg/dL contribute to diagnosis of deficiency of G6PD, Hydrogen peroxidases Causes Extravascular Hemolysis, Unconjugated Bilirubin causing Total Serum Bilirubin 19 mg/dL, erythropoiesis leads to increased Reticulocyte Count 262 x 10^9/L, hydrogen peroxide to 2 H20, Cytochrome P-450 necessary for detoxification of drugs, 2 Irriversible Oxidative Rxns Utilizes G6PD, glucathione peroxidase neutralizes hydrogen peroxide, Macrophages Causes release of hemoglobin, Extravascular Hemolysis releasing hemoglobin, Patient in Case 1 50 y/o Female Presents w/ Reticulocyte Count 262 x 10^9/L, Unconjugated Bilirubin When Increased can result in Jaundice, NADPH is needed by glucothione reductase, hemoglobin broken down in spleen to Heme, NADPH/NADP ratio when high inhibits G6PD